EP1993519A4 - Methods and compositions for deterring abuse of orally administered pharmaceutical products - Google Patents
Methods and compositions for deterring abuse of orally administered pharmaceutical productsInfo
- Publication number
- EP1993519A4 EP1993519A4 EP07753168A EP07753168A EP1993519A4 EP 1993519 A4 EP1993519 A4 EP 1993519A4 EP 07753168 A EP07753168 A EP 07753168A EP 07753168 A EP07753168 A EP 07753168A EP 1993519 A4 EP1993519 A4 EP 1993519A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- compositions
- methods
- orally administered
- pharmaceutical products
- administered pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1664—Compounds of unknown constitution, e.g. material from plants or animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2009—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78244806P | 2006-03-15 | 2006-03-15 | |
PCT/US2007/006519 WO2007106550A2 (en) | 2006-03-15 | 2007-03-14 | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1993519A2 EP1993519A2 (en) | 2008-11-26 |
EP1993519A4 true EP1993519A4 (en) | 2011-12-21 |
Family
ID=38510088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP07753168A Withdrawn EP1993519A4 (en) | 2006-03-15 | 2007-03-14 | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1993519A4 (en) |
AU (1) | AU2007225101A1 (en) |
CA (1) | CA2647360C (en) |
IL (1) | IL193766A0 (en) |
WO (1) | WO2007106550A2 (en) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
WO2003024429A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Polymer release system |
EP1610767B1 (en) | 2003-03-26 | 2011-01-19 | Egalet A/S | Morphine controlled release system |
CA2687192C (en) | 2007-06-04 | 2015-11-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
AU2008338442A1 (en) * | 2007-12-17 | 2009-06-25 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
AU2015200313B2 (en) * | 2007-12-17 | 2016-12-01 | Alpharma Pharmaceuticals, Llc | Pharmaceutical composition |
BRPI0821732A2 (en) | 2007-12-17 | 2015-06-16 | Labopharm Inc | Controlled release formulations, solid dosage form, and use of controlled release formulation |
AU2009327312A1 (en) | 2008-12-16 | 2011-08-04 | Labopharm Europe Limited | Misuse preventative, controlled release formulation |
WO2010089132A1 (en) | 2009-02-06 | 2010-08-12 | Egalet A/S | Immediate release composition resistant to abuse by intake of alcohol |
EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
KR20150059167A (en) | 2012-07-06 | 2015-05-29 | 에갈렛 리미티드 | Abuse deterrent pharmaceutical compositions for controlled release |
WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US9707184B2 (en) | 2014-07-17 | 2017-07-18 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
US9132096B1 (en) | 2014-09-12 | 2015-09-15 | Alkermes Pharma Ireland Limited | Abuse resistant pharmaceutical compositions |
US20160106737A1 (en) | 2014-10-20 | 2016-04-21 | Pharmaceutical Manufacturing Research Services, Inc. | Extended Release Abuse Deterrent Liquid Fill Dosage Form |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050214223A1 (en) * | 2002-10-25 | 2005-09-29 | Gruenenthal Gmbh | Abuse-safeguarded dosage form |
WO2006058249A2 (en) * | 2004-11-24 | 2006-06-01 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7201920B2 (en) * | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
US20060110327A1 (en) * | 2004-11-24 | 2006-05-25 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
-
2007
- 2007-03-14 AU AU2007225101A patent/AU2007225101A1/en not_active Abandoned
- 2007-03-14 EP EP07753168A patent/EP1993519A4/en not_active Withdrawn
- 2007-03-14 CA CA2647360A patent/CA2647360C/en not_active Expired - Fee Related
- 2007-03-14 WO PCT/US2007/006519 patent/WO2007106550A2/en active Application Filing
-
2008
- 2008-08-28 IL IL193766A patent/IL193766A0/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050214223A1 (en) * | 2002-10-25 | 2005-09-29 | Gruenenthal Gmbh | Abuse-safeguarded dosage form |
WO2006058249A2 (en) * | 2004-11-24 | 2006-06-01 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of orally administered pharmaceutical products |
Also Published As
Publication number | Publication date |
---|---|
IL193766A0 (en) | 2011-08-01 |
CA2647360C (en) | 2012-05-15 |
WO2007106550A2 (en) | 2007-09-20 |
AU2007225101A1 (en) | 2007-09-20 |
CA2647360A1 (en) | 2007-09-20 |
WO2007106550A3 (en) | 2008-06-12 |
EP1993519A2 (en) | 2008-11-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1993519A4 (en) | Methods and compositions for deterring abuse of orally administered pharmaceutical products | |
EP1817011A4 (en) | Methods and compositions for deterring abuse of orally administered pharmaceutical products | |
IL193762A (en) | Compounds useful in inhibiting dgat1-related disorders, pharmaceutical compositions comprising them and use thereof in preparation of medicaments | |
ZA200901110B (en) | Pharmaceutically acceptable solubilizing composition and pharmaceutical dosage from containing same | |
IL197275A0 (en) | Pharmaceutical compositions of clonazepam and methods of use thereof | |
AP2008004447A0 (en) | Orally absorbed pharmaceutical formulation and method of administration | |
IL194546A0 (en) | Arylaminopyridine derivatives and pharmaceutical compositions containing them | |
IL193727A0 (en) | Dosage forms for administering combinations of drugs | |
EP2099449A4 (en) | Pharmaceutical composition for the treatment and prevention of diseases involving impotence | |
IL194954A0 (en) | Cycloalkylamino acid derivatives and pharmaceutical compositions thereof | |
IL199853A (en) | Substituted derivatives of 5-hydroxy-adamantyl-2-yl and pharmaceutical compositions comprising them | |
ZA200900423B (en) | Methods and medicaments for administration of ibuprofen | |
PL2046312T3 (en) | Pharmaceutical and nutraceutical products comprising vitamin k2 | |
EP2086945A4 (en) | Novel process for the preparation of statins and their pharmaceutically acceptable salts thereof | |
AP2008004671A0 (en) | Cycloalkylamino acid derivatives and pharmaceutical compositions thereof | |
IL206835A (en) | Pharmaceutical compositions comprising oil and particulate matter for oral administration of insulin and methods for preparation thereof | |
HUS2000053I1 (en) | Quinolinone derivatives and their pharmaceutical compositions | |
IL193211A (en) | Indazole-heteroaryl derivatives and pharmaceutical compositions comprising them | |
IL178067A0 (en) | Pharmaceutical dosage forms and compositions | |
EP2051721A4 (en) | Preparation and pharmaceutical use of euterpe oleracea (acai) extract compositions | |
HK1131030A1 (en) | Packaging system for pharmaceutical compositions and kit for intravenous administration | |
EP1855647A4 (en) | Delayed release pharmaceutical oral dosage form and method of making same | |
IL191922A0 (en) | Pharmaceutical formulations of oxcarbazepine and methods for its preparation | |
PL2008655T3 (en) | Pharmaceutical composition that comprises an analgesic and vitamins | |
HUP0600097A3 (en) | Pharmaceutical compositions comprising tacrolimus and process for their preparation |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20080916 |
|
AK | Designated contracting states |
Kind code of ref document: A2 Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IS IT LI LT LU LV MC MT NL PL PT RO SE SI SK TR |
|
AX | Request for extension of the european patent |
Extension state: AL BA HR MK RS |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1121393 Country of ref document: HK |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20111117 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 45/06 20060101ALI20111111BHEP Ipc: A61K 9/16 20060101ALI20111111BHEP Ipc: A61K 9/50 20060101ALI20111111BHEP Ipc: A61K 9/20 20060101ALI20111111BHEP Ipc: A61K 31/485 20060101AFI20111111BHEP |
|
DAX | Request for extension of the european patent (deleted) | ||
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20120619 |
|
REG | Reference to a national code |
Ref country code: HK Ref legal event code: WD Ref document number: 1121393 Country of ref document: HK |