DE69934781D1 - Morphinsulfat enthaltende mikrogranulate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen - Google Patents
Morphinsulfat enthaltende mikrogranulate, verfahren zu deren herstellung und pharmazeutische zusammensetzungenInfo
- Publication number
- DE69934781D1 DE69934781D1 DE69934781T DE69934781T DE69934781D1 DE 69934781 D1 DE69934781 D1 DE 69934781D1 DE 69934781 T DE69934781 T DE 69934781T DE 69934781 T DE69934781 T DE 69934781T DE 69934781 D1 DE69934781 D1 DE 69934781D1
- Authority
- DE
- Germany
- Prior art keywords
- morphinsulfate
- microgranulates
- preparation
- pharmaceutical compositions
- pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9801816 | 1998-02-16 | ||
FR9801816A FR2774910B1 (fr) | 1998-02-16 | 1998-02-16 | Microgranules de sulfate de morphine, procede de fabrication et preparations pharmaceutiques |
PCT/FR1999/000326 WO1999040918A1 (fr) | 1998-02-16 | 1999-02-15 | Microgranules de sulfate de morphine, procede de fabrication et preparations pharmaceutiques |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69934781D1 true DE69934781D1 (de) | 2007-02-22 |
DE69934781T2 DE69934781T2 (de) | 2007-10-11 |
Family
ID=9522990
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69934781T Expired - Lifetime DE69934781T2 (de) | 1998-02-16 | 1999-02-15 | Morphinsulfat enthaltende mikrogranulate, verfahren zu deren herstellung und pharmazeutische zusammensetzungen |
Country Status (16)
Country | Link |
---|---|
US (2) | US6482437B2 (de) |
EP (1) | EP1054672B1 (de) |
JP (1) | JP4447166B2 (de) |
CN (1) | CN1135981C (de) |
AU (1) | AU2429899A (de) |
BR (1) | BR9907908A (de) |
CA (1) | CA2320878C (de) |
CY (1) | CY1107559T1 (de) |
DE (1) | DE69934781T2 (de) |
DK (1) | DK1054672T3 (de) |
ES (1) | ES2277427T3 (de) |
FR (1) | FR2774910B1 (de) |
HK (1) | HK1036402A1 (de) |
NZ (1) | NZ506307A (de) |
PT (1) | PT1054672E (de) |
WO (1) | WO1999040918A1 (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2790668B1 (fr) * | 1999-03-12 | 2002-07-26 | D B F | Granules contenant une substance vegetale et leur procede de preparation |
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
ATE495732T1 (de) | 2003-03-26 | 2011-02-15 | Egalet As | Morphin-system mit kontrollierter freisetzung |
CN1874764B (zh) * | 2003-10-10 | 2012-08-01 | 埃法尔姆公司 | 含有银杏提取物的持续释放微粒及其制备方法 |
FR2883179B1 (fr) | 2005-03-18 | 2009-04-17 | Ethypharm Sa | Comprime enrobe |
US20070190141A1 (en) * | 2006-02-16 | 2007-08-16 | Aaron Dely | Extended release opiate composition |
US20100233257A1 (en) * | 2006-06-09 | 2010-09-16 | Ethypharm | Low dose sublingual tablets of opioid analgesics and preparation process |
US20070286900A1 (en) * | 2006-06-09 | 2007-12-13 | Catherine Herry | Low dose tablets of opioid analgesics and preparation process |
EP2155167A2 (de) | 2007-06-04 | 2010-02-24 | Egalet A/S | Pharmazeutische zusammensetzungen mit gesteuerter freisetzung für verlängerte wirkung |
AU2008296971B2 (en) * | 2007-09-03 | 2014-10-02 | Nanoshift, Llc | Particulate compositions for delivery of poorly soluble drugs |
NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
NZ603579A (en) | 2009-06-24 | 2014-02-28 | Egalet Ltd | Controlled release formulations |
CA2877183A1 (en) | 2012-07-06 | 2014-01-09 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
US9683448B2 (en) | 2013-03-18 | 2017-06-20 | Honeywell International Inc. | Low conductivity thermal barrier coating |
US11479846B2 (en) | 2014-01-07 | 2022-10-25 | Honeywell International Inc. | Thermal barrier coatings for turbine engine components |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4142526A (en) * | 1974-12-23 | 1979-03-06 | Alza Corporation | Osmotic releasing system with means for changing release therefrom |
US4309996A (en) * | 1980-04-28 | 1982-01-12 | Alza Corporation | System with microporous releasing diffusor |
US4673405A (en) * | 1983-03-04 | 1987-06-16 | Alza Corporation | Osmotic system with instant drug availability |
US5026560A (en) * | 1987-01-29 | 1991-06-25 | Takeda Chemical Industries, Ltd. | Spherical granules having core and their production |
DE3708856A1 (de) | 1987-03-18 | 1988-09-29 | Kajetan Leitner | Mit zaehnen versehene einpressmutter |
US5202128A (en) * | 1989-01-06 | 1993-04-13 | F. H. Faulding & Co. Limited | Sustained release pharmaceutical composition |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
US5580578A (en) * | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US5891471A (en) * | 1993-11-23 | 1999-04-06 | Euro-Celtique, S.A. | Pharmaceutical multiparticulates |
US5411745A (en) * | 1994-05-25 | 1995-05-02 | Euro-Celtique, S.A. | Powder-layered morphine sulfate formulations |
US5582838A (en) * | 1994-12-22 | 1996-12-10 | Merck & Co., Inc. | Controlled release drug suspension delivery device |
US6066339A (en) * | 1997-10-17 | 2000-05-23 | Elan Corporation, Plc | Oral morphine multiparticulate formulation |
-
1998
- 1998-02-16 FR FR9801816A patent/FR2774910B1/fr not_active Expired - Lifetime
-
1999
- 1999-02-15 ES ES99903752T patent/ES2277427T3/es not_active Expired - Lifetime
- 1999-02-15 DK DK99903752T patent/DK1054672T3/da active
- 1999-02-15 EP EP99903752A patent/EP1054672B1/de not_active Expired - Lifetime
- 1999-02-15 AU AU24298/99A patent/AU2429899A/en not_active Abandoned
- 1999-02-15 JP JP2000531170A patent/JP4447166B2/ja not_active Expired - Lifetime
- 1999-02-15 WO PCT/FR1999/000326 patent/WO1999040918A1/fr active IP Right Grant
- 1999-02-15 PT PT99903752T patent/PT1054672E/pt unknown
- 1999-02-15 CN CNB998030120A patent/CN1135981C/zh not_active Expired - Lifetime
- 1999-02-15 DE DE69934781T patent/DE69934781T2/de not_active Expired - Lifetime
- 1999-02-15 NZ NZ506307A patent/NZ506307A/en not_active IP Right Cessation
- 1999-02-15 CA CA002320878A patent/CA2320878C/fr not_active Expired - Lifetime
- 1999-02-15 BR BR9907908-9A patent/BR9907908A/pt not_active Application Discontinuation
- 1999-02-16 US US09/250,393 patent/US6482437B2/en not_active Expired - Lifetime
-
2001
- 2001-10-11 HK HK01107153A patent/HK1036402A1/xx not_active IP Right Cessation
-
2002
- 2002-09-30 US US10/259,854 patent/US20030129244A1/en not_active Abandoned
-
2007
- 2007-02-20 CY CY20071100242T patent/CY1107559T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
NZ506307A (en) | 2003-11-28 |
US6482437B2 (en) | 2002-11-19 |
DE69934781T2 (de) | 2007-10-11 |
DK1054672T3 (da) | 2007-04-10 |
PT1054672E (pt) | 2007-04-30 |
AU2429899A (en) | 1999-08-30 |
JP2002502877A (ja) | 2002-01-29 |
BR9907908A (pt) | 2002-04-30 |
CN1291097A (zh) | 2001-04-11 |
US20030129244A1 (en) | 2003-07-10 |
JP4447166B2 (ja) | 2010-04-07 |
EP1054672B1 (de) | 2007-01-10 |
FR2774910B1 (fr) | 2001-09-07 |
CN1135981C (zh) | 2004-01-28 |
CY1107559T1 (el) | 2013-03-13 |
EP1054672A1 (de) | 2000-11-29 |
CA2320878C (fr) | 2009-04-21 |
CA2320878A1 (fr) | 1999-08-19 |
ES2277427T3 (es) | 2007-07-01 |
US20020028246A1 (en) | 2002-03-07 |
HK1036402A1 (en) | 2002-01-04 |
FR2774910A1 (fr) | 1999-08-20 |
WO1999040918A1 (fr) | 1999-08-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |