DE60320039D1 - Tramadol-formulierungen mit verzögerter freisetzung und 24-stunden-wirksamkeit - Google Patents

Tramadol-formulierungen mit verzögerter freisetzung und 24-stunden-wirksamkeit

Info

Publication number
DE60320039D1
DE60320039D1 DE60320039T DE60320039T DE60320039D1 DE 60320039 D1 DE60320039 D1 DE 60320039D1 DE 60320039 T DE60320039 T DE 60320039T DE 60320039 T DE60320039 T DE 60320039T DE 60320039 D1 DE60320039 D1 DE 60320039D1
Authority
DE
Germany
Prior art keywords
delayed release
tramadol formulations
hour efficacy
efficacy
hour
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60320039T
Other languages
English (en)
Other versions
DE60320039T2 (de
Inventor
Vincent Lenaerts
Patricia Laure Ouadji-Njiki
Jonathan Bacon
Rachid Ouzerourou
Sonia Gervais
Miloud Rahmouni
Damon Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labopharm Barbados Ltd
Labopharm Inc
Paladin Labs Europe Ltd
Original Assignee
Labopharm Barbados Ltd
Labopharm Inc
Paladin Labs Europe Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labopharm Barbados Ltd, Labopharm Inc, Paladin Labs Europe Ltd filed Critical Labopharm Barbados Ltd
Priority claimed from PCT/CA2003/001638 external-priority patent/WO2004037222A2/en
Application granted granted Critical
Publication of DE60320039D1 publication Critical patent/DE60320039D1/de
Publication of DE60320039T2 publication Critical patent/DE60320039T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
DE60320039T 2002-10-25 2003-10-27 Tramadol-formulierungen mit verzögerter freisetzung und 24-stunden-wirksamkeit Expired - Lifetime DE60320039T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US50906202P 2002-10-25 2002-10-25
US509062P 2002-10-25
US51037803P 2003-10-10 2003-10-10
US510378P 2003-10-10
PCT/CA2003/001638 WO2004037222A2 (en) 2002-10-25 2003-10-27 Sustained-release tramadol formulations with 24-hour efficacy

Publications (2)

Publication Number Publication Date
DE60320039D1 true DE60320039D1 (de) 2008-05-08
DE60320039T2 DE60320039T2 (de) 2009-05-14

Family

ID=35044187

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60320039T Expired - Lifetime DE60320039T2 (de) 2002-10-25 2003-10-27 Tramadol-formulierungen mit verzögerter freisetzung und 24-stunden-wirksamkeit

Country Status (12)

Country Link
US (1) US7988998B2 (de)
EP (1) EP1594460B1 (de)
AT (1) ATE390128T1 (de)
BR (1) BR0315659A (de)
DE (1) DE60320039T2 (de)
DK (1) DK1594460T3 (de)
ES (1) ES2305567T3 (de)
HK (1) HK1101355A1 (de)
MX (1) MXPA05004412A (de)
NZ (1) NZ539870A (de)
SI (1) SI1594460T1 (de)
TW (1) TWI319713B (de)

Families Citing this family (12)

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RU2469718C2 (ru) * 2007-10-16 2012-12-20 Лабофарм Инк. Двухслойная композиция для непрерывного высвобождения ацетаминофена и трамадола
JP5651818B2 (ja) 2007-12-17 2015-01-14 パラディン ラブス インコーポレーテッド 誤用を防止するための放出制御製剤
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US8486449B2 (en) 2008-12-16 2013-07-16 Paladin Labs Inc. Misuse preventative, controlled release formulation
US8623409B1 (en) 2010-10-20 2014-01-07 Tris Pharma Inc. Clonidine formulation
KR102380825B1 (ko) * 2015-05-29 2022-04-01 삼성전자주식회사 반도체 발광다이오드 칩 및 이를 구비한 발광장치
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MXPA05004412A (es) 2005-11-23
SI1594460T1 (sl) 2008-08-31
TWI319713B (en) 2010-01-21
ES2305567T3 (es) 2008-11-01
HK1101355A1 (en) 2007-10-18
EP1594460A2 (de) 2005-11-16
BR0315659A (pt) 2005-09-20
ATE390128T1 (de) 2008-04-15
US20070003618A1 (en) 2007-01-04
DE60320039T2 (de) 2009-05-14
NZ539870A (en) 2007-11-30
US7988998B2 (en) 2011-08-02
EP1594460B1 (de) 2008-03-26
US20090047345A9 (en) 2009-02-19

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