DE502004010368D1 - Verfahren zur herstellung einer gegen missbrauch gesicherten darreichungsform - Google Patents

Verfahren zur herstellung einer gegen missbrauch gesicherten darreichungsform

Info

Publication number
DE502004010368D1
DE502004010368D1 DE502004010368T DE502004010368T DE502004010368D1 DE 502004010368 D1 DE502004010368 D1 DE 502004010368D1 DE 502004010368 T DE502004010368 T DE 502004010368T DE 502004010368 T DE502004010368 T DE 502004010368T DE 502004010368 D1 DE502004010368 D1 DE 502004010368D1
Authority
DE
Germany
Prior art keywords
misuse
aggregate
injury
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE502004010368T
Other languages
English (en)
Inventor
Johannes Bartholomaeus
Elisabeth Arkenau-Maric
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruenenthal GmbH
Original Assignee
Gruenenthal GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal GmbH filed Critical Gruenenthal GmbH
Publication of DE502004010368D1 publication Critical patent/DE502004010368D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/16—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses using pocketed rollers, e.g. two co-operating pocketed rollers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B30—PRESSES
    • B30B—PRESSES IN GENERAL
    • B30B11/00—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses
    • B30B11/34—Presses specially adapted for forming shaped articles from material in particulate or plastic state, e.g. briquetting presses, tabletting presses for coating articles, e.g. tablets
DE502004010368T 2003-12-24 2004-12-23 Verfahren zur herstellung einer gegen missbrauch gesicherten darreichungsform Active DE502004010368D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10361596A DE10361596A1 (de) 2003-12-24 2003-12-24 Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
PCT/EP2004/014679 WO2005063214A1 (de) 2003-12-24 2004-12-23 Verfahren zur herstellung einer gegen missbrauch gesicherten darreichungsform

Publications (1)

Publication Number Publication Date
DE502004010368D1 true DE502004010368D1 (de) 2009-12-24

Family

ID=34716231

Family Applications (2)

Application Number Title Priority Date Filing Date
DE10361596A Withdrawn DE10361596A1 (de) 2003-08-06 2003-12-24 Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE502004010368T Active DE502004010368D1 (de) 2003-12-24 2004-12-23 Verfahren zur herstellung einer gegen missbrauch gesicherten darreichungsform

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE10361596A Withdrawn DE10361596A1 (de) 2003-08-06 2003-12-24 Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform

Country Status (19)

Country Link
US (6) US20070003616A1 (de)
EP (1) EP1699440B1 (de)
JP (1) JP4895821B2 (de)
CN (1) CN1917862B (de)
AR (1) AR046994A1 (de)
AT (1) ATE447942T1 (de)
AU (1) AU2004308653B2 (de)
CA (1) CA2551231A1 (de)
CY (1) CY1110609T1 (de)
DE (2) DE10361596A1 (de)
DK (1) DK1699440T3 (de)
ES (1) ES2336571T3 (de)
HK (1) HK1099511A1 (de)
IL (1) IL176296A0 (de)
PE (1) PE20050814A1 (de)
PL (1) PL1699440T3 (de)
PT (1) PT1699440E (de)
SI (1) SI1699440T1 (de)
WO (1) WO2005063214A1 (de)

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US20170049706A1 (en) 2017-02-23
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CN1917862A (zh) 2007-02-21
EP1699440B1 (de) 2009-11-11
JP2007516998A (ja) 2007-06-28
US20160367487A1 (en) 2016-12-22
US11224576B2 (en) 2022-01-18
DE10361596A1 (de) 2005-09-29
AU2004308653B2 (en) 2009-09-03
US20150164811A1 (en) 2015-06-18
AR046994A1 (es) 2006-01-04
WO2005063214A1 (de) 2005-07-14
ES2336571T3 (es) 2010-04-14
US20090005408A1 (en) 2009-01-01
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EP1699440A1 (de) 2006-09-13
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CA2551231A1 (en) 2005-07-14
HK1099511A1 (en) 2007-08-17
SI1699440T1 (sl) 2010-03-31
IL176296A0 (en) 2006-10-05
CN1917862B (zh) 2011-08-03
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US20070003616A1 (en) 2007-01-04
ATE447942T1 (de) 2009-11-15

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