CN103476403A - 阿片样物质的控释制剂 - Google Patents
阿片样物质的控释制剂 Download PDFInfo
- Publication number
- CN103476403A CN103476403A CN2011800562785A CN201180056278A CN103476403A CN 103476403 A CN103476403 A CN 103476403A CN 2011800562785 A CN2011800562785 A CN 2011800562785A CN 201180056278 A CN201180056278 A CN 201180056278A CN 103476403 A CN103476403 A CN 103476403A
- Authority
- CN
- China
- Prior art keywords
- oxycodone
- salt
- opioid
- pharmaceutical preparation
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US38622710P | 2010-09-24 | 2010-09-24 | |
US61/386,227 | 2010-09-24 | ||
US13/024,319 US20110195989A1 (en) | 2010-02-09 | 2011-02-09 | Controlled Release Formulations of Opioids |
US13/024,319 | 2011-02-09 | ||
PCT/US2011/053132 WO2012040651A2 (fr) | 2010-09-24 | 2011-09-23 | Formulations d'opioïdes à libération contrôlée |
Publications (1)
Publication Number | Publication Date |
---|---|
CN103476403A true CN103476403A (zh) | 2013-12-25 |
Family
ID=44741728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN2011800562785A Pending CN103476403A (zh) | 2010-09-24 | 2011-09-23 | 阿片样物质的控释制剂 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP2618820A2 (fr) |
JP (1) | JP2013537915A (fr) |
CN (1) | CN103476403A (fr) |
AU (1) | AU2011305161A1 (fr) |
CA (1) | CA2812570A1 (fr) |
WO (1) | WO2012040651A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114515282A (zh) * | 2020-11-19 | 2022-05-20 | 山东大学 | Sorbic acid在制备抗冠状病毒感染药物中的应用 |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040234602A1 (en) | 2001-09-21 | 2004-11-25 | Gina Fischer | Polymer release system |
US20040253310A1 (en) | 2001-09-21 | 2004-12-16 | Gina Fischer | Morphine polymer release system |
ES2360102T3 (es) | 2003-03-26 | 2011-05-31 | Egalet A/S | Sistema para la liberación controlada de morfina. |
AU2008258596B2 (en) | 2007-06-04 | 2013-02-14 | Egalet Ltd | Controlled release pharmaceutical compositions for prolonged effect |
NZ594207A (en) | 2009-02-06 | 2013-03-28 | Egalet Ltd | Immediate release composition resistant to abuse by intake of alcohol |
EP2445487A2 (fr) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Formulations à libération contrôlée |
WO2013153451A2 (fr) * | 2012-04-09 | 2013-10-17 | QRxPharma Ltd. | Formulations d'opioïdes à libération contrôlée |
EP2877161A1 (fr) | 2012-07-06 | 2015-06-03 | Egalet Ltd. | Compositions pharmaceutiques de dissuasion d'abus à libération contrôlée |
EP3169315B1 (fr) * | 2014-07-17 | 2020-06-24 | Pharmaceutical Manufacturing Research Services, Inc. | Forme posologique remplie de liquide anti-abus à libération immédiate |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2003039561A1 (fr) * | 2001-11-02 | 2003-05-15 | Elan Corporation, Plc | Composition pharmaceutique |
US20060240105A1 (en) * | 1998-11-02 | 2006-10-26 | Elan Corporation, Plc | Multiparticulate modified release composition |
CN101151021A (zh) * | 2005-03-28 | 2008-03-26 | 奥瑞克索股份公司 | 用于疼痛治疗的新药物组合物 |
CN101534827A (zh) * | 2006-11-07 | 2009-09-16 | 尼克塔治疗亚拉巴马公司 | 阿片样物质激动剂和阿片样物质拮抗剂的剂型和联合给药 |
US20090291975A1 (en) * | 2008-05-20 | 2009-11-26 | Warren Stern | Dual opioid pain therapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
US6419960B1 (en) * | 1998-12-17 | 2002-07-16 | Euro-Celtique S.A. | Controlled release formulations having rapid onset and rapid decline of effective plasma drug concentrations |
UA81224C2 (uk) * | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
US20030092724A1 (en) * | 2001-09-18 | 2003-05-15 | Huaihung Kao | Combination sustained release-immediate release oral dosage forms with an opioid analgesic and a non-opioid analgesic |
US8906413B2 (en) * | 2003-05-12 | 2014-12-09 | Supernus Pharmaceuticals, Inc. | Drug formulations having reduced abuse potential |
AU2005323534A1 (en) | 2005-01-05 | 2006-07-13 | Philip S. Portoghese | Analgesic conjugates |
WO2007087452A2 (fr) | 2006-01-27 | 2007-08-02 | Theraquest Biosciences, Llc | Formulations à libération prolongée empêchant l'usage abusif et méthodes d'utilisation de celles-ci |
US20110195989A1 (en) * | 2010-02-09 | 2011-08-11 | Rudnic Edward M | Controlled Release Formulations of Opioids |
-
2011
- 2011-09-23 JP JP2013530379A patent/JP2013537915A/ja active Pending
- 2011-09-23 CN CN2011800562785A patent/CN103476403A/zh active Pending
- 2011-09-23 CA CA2812570A patent/CA2812570A1/fr not_active Abandoned
- 2011-09-23 AU AU2011305161A patent/AU2011305161A1/en not_active Abandoned
- 2011-09-23 WO PCT/US2011/053132 patent/WO2012040651A2/fr active Application Filing
- 2011-09-23 EP EP11764653.9A patent/EP2618820A2/fr not_active Withdrawn
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060240105A1 (en) * | 1998-11-02 | 2006-10-26 | Elan Corporation, Plc | Multiparticulate modified release composition |
WO2003039561A1 (fr) * | 2001-11-02 | 2003-05-15 | Elan Corporation, Plc | Composition pharmaceutique |
CN101151021A (zh) * | 2005-03-28 | 2008-03-26 | 奥瑞克索股份公司 | 用于疼痛治疗的新药物组合物 |
CN101534827A (zh) * | 2006-11-07 | 2009-09-16 | 尼克塔治疗亚拉巴马公司 | 阿片样物质激动剂和阿片样物质拮抗剂的剂型和联合给药 |
US20090291975A1 (en) * | 2008-05-20 | 2009-11-26 | Warren Stern | Dual opioid pain therapy |
Non-Patent Citations (1)
Title |
---|
CARLA RIPAMONTI1.ET AL: "Strategies for the Treatment of Cancer", 《DRUGS》, vol. 61, no. 7, 31 December 2001 (2001-12-31), pages 955 - 977 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114515282A (zh) * | 2020-11-19 | 2022-05-20 | 山东大学 | Sorbic acid在制备抗冠状病毒感染药物中的应用 |
CN114515282B (zh) * | 2020-11-19 | 2023-09-08 | 山东大学 | Sorbic acid在制备抗冠状病毒感染药物中的应用 |
Also Published As
Publication number | Publication date |
---|---|
EP2618820A2 (fr) | 2013-07-31 |
WO2012040651A3 (fr) | 2012-05-18 |
JP2013537915A (ja) | 2013-10-07 |
CA2812570A1 (fr) | 2012-03-29 |
AU2011305161A1 (en) | 2013-05-09 |
WO2012040651A2 (fr) | 2012-03-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20131225 |