CA2059855A1 - Controlled release compositions - Google Patents

Controlled release compositions

Info

Publication number
CA2059855A1
CA2059855A1 CA002059855A CA2059855A CA2059855A1 CA 2059855 A1 CA2059855 A1 CA 2059855A1 CA 002059855 A CA002059855 A CA 002059855A CA 2059855 A CA2059855 A CA 2059855A CA 2059855 A1 CA2059855 A1 CA 2059855A1
Authority
CA
Canada
Prior art keywords
controlled release
release compositions
crenellations
suppositories
release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002059855A
Other languages
French (fr)
Other versions
CA2059855C (en
Inventor
Steven Robertson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BTG International Ltd
Original Assignee
Steven Robertson
British Technology Group P.L.C.
British Technology Group Limited
Btg International Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Steven Robertson, British Technology Group P.L.C., British Technology Group Limited, Btg International Limited filed Critical Steven Robertson
Publication of CA2059855A1 publication Critical patent/CA2059855A1/en
Application granted granted Critical
Publication of CA2059855C publication Critical patent/CA2059855C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/08—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of suppositories or sticks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms

Abstract

Controlled release compositions comprising a water sweliable carrier and an active material having crenellated surface exhibit improved release properties. Suppositories and pessaries of generally cylindrical shape having four or five crenellations spaced equally around the perimeter and extending substantially along the length of the cylinder are preferred.
Suppositories comprising four or five rounded crenellations which release morphine sulphate are especially useful.
CA002059855A 1991-01-23 1992-01-22 Controlled release compositions Expired - Lifetime CA2059855C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919101502A GB9101502D0 (en) 1991-01-23 1991-01-23 Controlled release compositions
GB9101502.4 1991-01-23

Publications (2)

Publication Number Publication Date
CA2059855A1 true CA2059855A1 (en) 1992-07-24
CA2059855C CA2059855C (en) 2002-03-05

Family

ID=10688907

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002059855A Expired - Lifetime CA2059855C (en) 1991-01-23 1992-01-22 Controlled release compositions

Country Status (10)

Country Link
US (1) US5352455A (en)
JP (1) JP3296579B2 (en)
KR (1) KR0123625Y1 (en)
CA (1) CA2059855C (en)
DE (1) DE9200765U1 (en)
ES (1) ES1021151Y (en)
FR (1) FR2671726B3 (en)
GB (2) GB9101502D0 (en)
PT (1) PT100047B (en)
ZA (1) ZA92477B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5342624A (en) * 1989-02-16 1994-08-30 British Technology Group Ltd. Dispensing device
GB2254002B (en) * 1991-01-16 1995-03-22 Controlled Therapeutics Retrievable pessary
GB9612370D0 (en) * 1996-06-13 1996-08-14 Whitehall Lab Ltd A novel suppository
DE19734538C1 (en) * 1997-07-30 1998-12-24 Jenapharm Gmbh Bioadhesive tablet
DE19814014A1 (en) * 1997-12-19 1999-09-30 Krewel Meuselbach Gmbh Medicinal plant dry extracts
US6720356B2 (en) * 2001-04-20 2004-04-13 Spencer Feldman Magnesium di-potassium EDTA complex and method of administration
WO2003024429A1 (en) 2001-09-21 2003-03-27 Egalet A/S Polymer release system
US20040253310A1 (en) 2001-09-21 2004-12-16 Gina Fischer Morphine polymer release system
EP1610767B1 (en) 2003-03-26 2011-01-19 Egalet A/S Morphine controlled release system
WO2006038080A2 (en) * 2004-10-01 2006-04-13 Clearlab International Pte. Ltd. Contact lens package solution
CA2687192C (en) 2007-06-04 2015-11-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
WO2010089132A1 (en) 2009-02-06 2010-08-12 Egalet A/S Immediate release composition resistant to abuse by intake of alcohol
EP2445487A2 (en) 2009-06-24 2012-05-02 Egalet Ltd. Controlled release formulations
KR20150059167A (en) 2012-07-06 2015-05-29 에갈렛 리미티드 Abuse deterrent pharmaceutical compositions for controlled release
USD765828S1 (en) 2015-02-19 2016-09-06 Crossford International, Llc Chemical tablet

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3114371A (en) * 1960-03-11 1963-12-17 Joseph F Montague Suppository
GB1142325A (en) * 1965-05-14 1969-02-05 Higham Stanley Russell Means for administering drugs
GB1154318A (en) * 1965-10-21 1969-06-04 Higham Stanley Russell Improvements in Vitamin B12 Compositions
CH502891A (en) * 1967-11-21 1971-02-15 Ciba Geigy Ag Technical, notched tablet
DE1814142A1 (en) * 1967-12-13 1969-07-31 Lokomotivbau Elektrotech Device for vapor deposition in a vacuum of large areas
US3927194A (en) * 1972-12-06 1975-12-16 Ives Lab Inc Tablet formulation
DE2401361C3 (en) * 1974-01-11 1978-06-08 Abbott Laboratories, Chicago, Ill. (V.St.A.) Drug carrier anchor to remain in body cavities
US4218433A (en) * 1977-03-03 1980-08-19 Nippon Kayaku Kabushiki Kaisha Constant-rate eluting tablet and method of producing same
WO1980001984A1 (en) * 1979-03-21 1980-10-02 M Embrey Controlled release compositions
US5079009A (en) * 1979-03-21 1992-01-07 National Research Development Corporation Controlled release compositions including polyethylene oxide with urethane cross-linking
US4258027A (en) * 1979-03-26 1981-03-24 Mead Johnson & Company Multi-fractionable tablet structure
US4353887A (en) * 1979-08-16 1982-10-12 Ciba-Geigy Corporation Divisible tablet having controlled and delayed release of the active substance
US4454309A (en) * 1980-11-12 1984-06-12 Tyndale Plains-Hunter, Ltd. Polyurethane polyene compositions
ZA813205B (en) * 1980-12-05 1983-03-30 Smith Kline French Lab Dosage units
GB2090535B (en) * 1981-01-06 1984-09-19 Osman Mohammad Fekry Medical inserts
US4503031A (en) * 1982-12-17 1985-03-05 Glassman Jacob A Super-fast-starting-sustained release tablet
GB2150938B (en) * 1983-12-05 1987-04-23 Tyndale Plains Hunter Limited Hydrophilic polyurethane acrylate compositions
US4769027A (en) * 1984-08-15 1988-09-06 Burroughs Wellcome Co. Delivery system
CA1273872A (en) * 1985-05-10 1990-09-11 Larry J. Caldwell Drug delivery device which can be retained in the stomach for a controlled period of time
US4767627A (en) * 1985-05-29 1988-08-30 Merck & Co., Inc. Drug delivery device which can be retained in the stomach for a controlled period of time
DE3532692A1 (en) * 1985-09-13 1987-03-19 Boehringer Mannheim Gmbh METHOD FOR PRODUCING TABLETS FROM PELLETS
DE3545090C1 (en) * 1985-12-19 1987-06-25 Capsoid Pharma Gmbh Process for the production of individually dosed dosage forms
US4824677A (en) * 1986-12-18 1989-04-25 The Unjohn Company Grooved tablet for fractional dosing of sustained release medication
KR900700071A (en) * 1987-12-17 1990-08-11 로버어트 에이 아미테이지 Tri-scored Drug Tablets
US4837111A (en) * 1988-03-21 1989-06-06 Alza Corporation Dosage form for dispensing drug for human therapy
US5009896A (en) * 1989-10-04 1991-04-23 Akzo N.V. Multi-fractionable tablet structure

Also Published As

Publication number Publication date
PT100047B (en) 1995-07-18
ES1021151Y (en) 1993-03-16
PT100047A (en) 1993-02-26
JPH04295418A (en) 1992-10-20
US5352455A (en) 1994-10-04
DE9200765U1 (en) 1992-04-16
GB9201355D0 (en) 1992-03-11
ES1021151U (en) 1992-10-16
FR2671726B3 (en) 1992-12-18
KR0123625Y1 (en) 1998-08-17
GB9101502D0 (en) 1991-03-06
JP3296579B2 (en) 2002-07-02
GB2252043A (en) 1992-07-29
CA2059855C (en) 2002-03-05
FR2671726A3 (en) 1992-07-24
ZA92477B (en) 1992-10-28
GB2252043B (en) 1994-10-12
KR920014773U (en) 1992-08-14

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Legal Events

Date Code Title Description
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